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1

Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer

Garon, Edward B., Rizvi, Naiyer A., Hui, Rina, Leighl, Natasha, Balmanoukian, Ani S., Eder, Joseph Paul, Patnaik, Amita, Aggarwal, Charu, Gubens, Matthew, Horn, Leora, Carcereny, Enric, Ahn, Myung-Ju,

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 974 KB

english, 2015

2

Hyperprogressive disease in early-phase immunotherapy trials: Clinical predictors and association with immune-related toxicities

Kanjanapan, Yada, Day, Daphne, Wang, Lisa, Al-Sawaihey, Hamad, Abbas, Engy, Namini, Amirali, Siu, Lillian L., Hansen, Aaron, Razak, Albiruni Abdul, Spreafico, Anna, Leighl, Natasha, Joshua, Anthony M.

Journal:

Year:

2019

Language:

english

File:

PDF, 459 KB

english, 2019

3

The role of cytology in molecular testing and personalized medicine in lung cancer: A clinical perspective

Young, Kelvin, da Cunha Santos, Gilda, Card, Paul, Leighl, Natasha

Journal:

Cancer Cytopathology

Year:

2018

Language:

english

File:

PDF, 183 KB

english, 2018

4

Five-Year Overall Survival for Patients With Advanced Non‒Small-Cell Lung Cancer Treated With Pembrolizumab: Results From the Phase I KEYNOTE-001 Study

Garon, Edward B., Hellmann, Matthew D., Rizvi, Naiyer A., Carcereny, Enric, Leighl, Natasha B., Ahn, Myung-Ju, Eder, Joseph Paul, Balmanoukian, Ani S., Aggarwal, Charu, Horn, Leora, Patnaik, Amita, Gu

Journal:

Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 797 KB

english, 2019

5

Death anxiety in patients with metastatic non-small cell lung cancer with and without brain metastases

Eggen, Annemarie C., Reyners, Anna K.L., Shen, Gerald, Bosma, Ingeborg, Jalving, Mathilde, Leighl, Natasha B., Liu, Geoffrey, Richard, Nadine M., Mah, Kenneth, Shultz, David B., Edelstein, Kim, Rodin,

Journal:

Journal of Pain and Symptom Management

Year:

2020

File:

PDF, 963 KB

2020

6

Mechanisms of osimertinib resistance and emerging treatment options

Schmid, Sabine, Li, Janice J.N., Leighl, Natasha B.

Journal:

Year:

2020

File:

PDF, 1.10 MB

2020

7

Determinants of quality of life in patients with advanced cancer

Camilla Zimmermann, Debika Burman, Nadia Swami, Monika K. Krzyzanowska, Natasha Leighl, Malcolm Moore, Gary Rodin, Ian Tannock

Journal:

Supportive Care in Cancer

Year:

2011

Language:

english

File:

PDF, 164 KB

english, 2011

8

Development and evaluation of a decision aid for patients considering first-line chemotherapy for metastatic breast cancer

Kimberly S. Chiew, Heather Shepherd, Janette Vardy, Martin H.N. Tattersall, Phyllis N. Butow, Natasha B. Leighl

Journal:

Health Expectations

Year:

2008

Language:

english

File:

PDF, 430 KB

english, 2008

9

Clinical Outcomes of Extensive Stage Small Cell Lung Carcinoma Patients Treated With Consolidative Thoracic Radiotherapy

Meredith E. Giuliani, Soha Atallah, Alexander Sun, Andrea Bezjak, Lisa W. Le, Anthony Brade, John Cho, Natasha B. Leighl, Frances A. Shepherd, Andrew J. Hope

Journal:

Clinical Lung Cancer

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

10

P-331 For richer, for poorer: A willingness-to-pay study of oral epidermal growth factor tyrosine kinase inhibitors in advanced non-small cell lung cancer

Leighl, N., Tsao, S., Zawisza, D., Nematollahi, M., Shepherd, F.

Journal:

Year:

2005

Language:

english

File:

PDF, 135 KB

english, 2005

11

Supporting Treatment Decision Making in Advanced Cancer: A Randomized Trial of a Decision Aid for Patients With Advanced Colorectal Cancer Considering Chemotherapy

Leighl, N. B., Shepherd, H. L., Butow, P. N., Clarke, S. J., McJannett, M., Beale, P. J., Wilcken, N. R. C., Moore, M. J., Chen, E. X., Goldstein, D., Horvath, L., Knox, J. J., Krzyzanowska, M., Oza,

Journal:

Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 260 KB

english, 2011

12

The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer

Peters, Solange, Bexelius, Christin, Munk, Veronica, Leighl, Natasha

Journal:

Cancer Treatment Reviews

Year:

2016

Language:

english

File:

PDF, 480 KB

english, 2016

13

Monitoring and Management of Immune-Related Adverse Events Associated With Programmed Cell Death Protein-1 Axis Inhibitors in Lung Cancer

OKane, G. M., Labbe, C., Doherty, M. K., Young, K., Albaba, H., Leighl, N. B.

Journal:

Year:

2016

Language:

english

File:

PDF, 1017 KB

english, 2016

14

Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non–Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

Leighl, Natasha B., Rizvi, Naiyer A., de Lima, Lopes Gilberto, Arpornwirat, Wichit, Rudin, Charles M., Chiappori, Alberto A., Ahn, Myung-Ju, Chow, Laura Q.M., Bazhenova, Lyudmila, Dechaphunkul, Arunee

Journal:

Clinical Lung Cancer

Year:

2016

Language:

english

File:

PDF, 507 KB

english, 2016

15

P2.39: Long-Term OS for Patients With Advanced NSCLC Enrolled in the KEYNOTE-001 Study of Pembrolizumab

Ramalingam, Suresh, Hui, Rina, Gandhi, Leena, Carcereny, Enric, Felip, Enriqueta, Ahn, Myung-Ju, Eder, Joseph P., Balmanoukian, Ani S., Leighl, Natasha, Aggarwal, Charu, Horn, Leora, Patnaik, Amita, M

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 106 KB

english, 2016

16

Systemic Therapy of Lung Cancer CNS Metastases Using Molecularly Targeted Agents and Immune Checkpoint Inhibitors

O’Kane, Grainne M., Leighl, Natasha B.

Journal:

Year:

2018

Language:

english

File:

PDF, 576 KB

english, 2018

17

Rationale and Protocol for a Canadian Multicenter Phase II Randomized Trial Assessing Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non–small-cell Lung Cancer (NCT02788461)

Raman, Srinivas, Bissonnette, Jean-Pierre, Warner, Andrew, Le, Lisa, Bratman, Scott, Leighl, Natasha, Bezjak, Andrea, Palma, David, Schellenberg, Devin, Sun, Alexander

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 524 KB

english, 2018

18

Economic analysis of osimertinib in previously untreated EGFR-mutant advanced non-small cell lung cancer in Canada

Ezeife, Doreen A., Kirk, Veronica, Chew, Derek S., Nixon, Nancy A., Lee, Roy, Le, Lisa W., Chan, Kelvin K.-W., Leighl, Natasha B.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

19

The Role of Angiogenesis Inhibitors in the Era of Immune Checkpoint Inhibitors and Targeted Therapy in Metastatic Non-Small Cell Lung Cancer

Perdrizet, Kirstin, Leighl, Natasha B.

Journal:

Current Treatment Options in Oncology

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

20

Improving lung cancer diagnosis: the evolving role of patients and care providers

Sung, Mike R., Leighl, Natasha B.

Journal:

Journal of Thoracic Disease

Year:

2019

Language:

english

File:

PDF, 118 KB

english, 2019

21

Emerging therapies for non-small cell lung cancer

Zhang, Chao, Leighl, Natasha B., Wu, Yi-Long, Zhong, Wen-Zhao

Journal:

Journal of Hematology & Oncology

Year:

2019

Language:

english

File:

PDF, 2.07 MB

english, 2019

22

Immune Checkpoint-Inhibitors and Chemoradiation in Stage III Unresectable Non-Small Cell Lung Cancer

Melosky, Barbara, Juergens, Rosalyn, McLeod, Deanna, Leighl, Natasha, Brade, Anthony, Card, Paul B., Chu, Quincy

Journal:

Year:

2019

Language:

english

File:

PDF, 719 KB

english, 2019

23

MA14.06 Predictors of Financial Toxicity, an Under-Recognized Patient-Reported Outcome

Ezeife, D., Morganstein, J., Lau, S., Law, J., Le, L., Bradbury, P., Liu, G., Shepherd, F., Leighl, N.

Journal:

Journal of Thoracic Oncology

Year:

2018

File:

PDF, 265 KB

2018

24

RADI-08. A SURVEY BASED STUDY OF BRAIN METASTASES MANAGEMENT FOR PATIENTS WITH NON-SMALL CELL LUNG CANCERS OR MELANOMA

Fong, Chin Heng, Leighl, Natasha, Butler, Marcus, Doherty, Mark, Kruser, Timothy, Shultz, David

Journal:

Neuro-Oncology Advances

Year:

2019

File:

PDF, 137 KB

2019

25

Lung Cancer Surveillance After Definitive Curative-Intent Therapy: ASCO Guideline

Schneider, Bryan J., Ismaila, Nofisat, Aerts, Joachim, Chiles, Caroline, Daly, Megan E., Detterbeck, Frank C., Hearn, Jason W.D., Katz, Sharyn I., Leighl, Natasha B., Levy, Benjamin, Meyers, Bryan, Mu

Journal:

Journal of Clinical Oncology

Year:

2019

File:

PDF, 583 KB

2019

26

Development of the Functional Assessment of Cancer Therapy–Immune Checkpoint Modulator (FACT‐ICM): A toxicity subscale to measure quality of life in patients with cancer who are treated with ICMs

Hansen, Aaron R., Ala‐Leppilampi, Kari, McKillop, Chris, Siu, Lillian L., Bedard, Philippe L., Abdul Razak, Albiruni R., Spreafico, Anna, Sridhar, Srikala S., Leighl, Natasha, Butler, Marcus O., Hogg,

Journal:

Year:

2020

Language:

english

File:

PDF, 244 KB

english, 2020

27

Advancing the systemic therapy of lung cancer: quality or quantity?

Fung, Andrea S, Leighl, Natasha B

Journal:

The Lancet Oncology

Year:

2020

File:

PDF, 138 KB

2020

28

Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study

Tan, Daniel S-W, Leighl, Natasha B, Riely, Gregory J, Yang, James C-H, Sequist, Lecia V, Wolf, Juergen, Seto, Takashi, Felip, Enriqueta, Aix, Santiago P, Jonnaert, Maud, Pan, Chun, Tan, Eugene Y, Ko,

Journal:

The Lancet Respiratory Medicine

Year:

2020

Language:

english

File:

PDF, 1.12 MB

english, 2020

29

Molecular testing for lung adenocarcinoma: Is it time to adopt a âplasmaâfirstâ approach?

Makarem, Maisam, Leighl, Natasha B.

Journal:

Year:

2020

File:

PDF, 134 KB

2020

30

Multicenter Validation Study to Implement Plasma Epidermal Growth Factor Receptor T790M Testing in Clinical Laboratories

Leighl, Natasha B., Kamel-Reid, Suzanne, Cheema, Parneet K., Laskin, Janessa, Karsan, Aly, Zhang, Tong, Stockley, Tracy, Barnes, Tristan A., Tudor, Roxana A., Liu, Geoffrey, Owen, Scott, Rothenstein,

Journal:

JCO Precision Oncology

Year:

2020

File:

PDF, 672 KB

2020

31

Correlation of immune-related adverse events and response from immune checkpoint inhibitors in patients with advanced non-small cell lung cancer

Sung, Mike, Zer, Alona, Walia, Preet, Khoja, Leila, Maganti, Manjula, Labbe, Catherine, Shepherd, Frances A., Bradbury, Penelope A., Liu, Geoffrey, Leighl, Natasha B.

Journal:

Journal of Thoracic Disease

Year:

2020

File:

PDF, 257 KB

2020

32

Metabolites as Prognostic Markers for Metastatic Non-Small Cell Lung Cancer (NSCLC) Patients Treated with First-Line Platinum-Doublet Chemotherapy

Hao, DesirÃ©e, Sengupta, Arjun, Ding, Keyue, Ubeydullah, ER, Krishnaiah, Saikumari, Leighl, Natasha B., Shepherd, Frances A., Seymour, Lesley, Weljie, Aalim

Journal:

Year:

2020

File:

PDF, 1.46 MB

2020

33

Can Oncologists Predict the Efficacy of Treatments in Randomized Trials?

Benjamin, Daniel M., Mandel, David R., Barnes, Tristan, Krzyzanowska, Monika K., Leighl, Natasha, Tannock, Ian F., Kimmelman, Jonathan

Journal:

Year:

2020

File:

PDF, 452 KB

2020

34

Venous thromboembolism and nonsmall cell lung cancer : A pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials

Lisa K. Hicks, Matthew C. Cheung, Keyue Ding, Baktiar Hasan, Lesley Seymour, Aurélie Le Maître, Natasha B. Leighl, Frances A. Shepherd

Journal:

Year:

2009

Language:

english

File:

PDF, 174 KB

english, 2009

35

Utilization of prophylactic cranial irradiation in patients with limited stage small cell lung carcinoma

Meredith Giuliani, Alexander Sun, Andrea Bezjak, Clement Ma, Lisa W. Le, Anthony Brade, John Cho, Natasha B. Leighl, Frances A. Shepherd, Andrew J. Hope

Journal:

Year:

2010

Language:

english

File:

PDF, 165 KB

english, 2010

36

EGFR gene status in cytological samples of nonsmall cell lung carcinoma : Controversies and opportunities

Gilda da Cunha Santos, Mauro Ajaj Saieg, William Geddie, Natasha Leighl

Journal:

Cancer Cytopathology

Year:

2011

Language:

english

File:

PDF, 319 KB

english, 2011

37

Survival Impact of Prophylactic Cranial Irradiation in Limited-stage Small-cell Lung Cancer

M.E. Giuliani, A. Hope, A. Sun, C. Ma, D. Payne, A. Brade, J. Cho, F. Shepherd, N. Leighl, A. Bezjak

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

38

Dosimetric and Clinical Parameters Contributing to Esophagitis and Radiation Pneumonitis following Treatment for Small-cell Lung Carcinoma

A.J. Hope, M. Giuliani, C. Ma, A. Bezjak, A. Sun, A. Brade, B.J. Cho, N. Leighl, F. Shepherd, P.E. Lindsay

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

39

Phase I Trial of Radiation With Concurrent and Consolidation Pemetrexed and Cisplatin in Patients With Unresectable Stage IIIA/B Non–Small-Cell Lung Cancer

Anthony Brade, Andrea Bezjak, Robert MacRae, Scott Laurie, Alex Sun, John Cho, Natasha Leighl, Shannon Pearson, Bernadette Southwood, Lisa Wang, Shauna McGill, Neill Iscoe, Frances A. Shepherd

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2011

Language:

english

File:

PDF, 104 KB

english, 2011

40

Patterns of Failure in Patients with Limited-Stage Small Cell Lung Carcinoma

Giuliani, M.E., Lindsay, P.E., Sun, A., Bezjak, A., Le, L.W., Brade, A., Cho, J., Leighl, N., Shepherd, F.A., Hope, A.J.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 34 KB

english, 2010

41

Outcomes of Bimodality and Trimodality Therapy in Patients with Stage III Non-small Cell Lung Cancer (NSCLC)

Hope, A.J., Coate, L.E., Massey, C., Sacher, A., Barrett, K., Keshavjee, S., Darling, G., Leighl, N.B., Bezjak, A., Shepherd, F.A.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

42

Determination of GTI-2040, a novel antisense oligonucleotide, in human plasma by using HPLC combined with solid phase and liquid–liquid extractions

Wenjiang Zhang, Natasha Leighl, Diane Zawisza, Malcolm J. Moore, Eric X. Chen

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

43

Treatment of lung cancer

Journal:

Critical Reviews in Oncology/Hematology

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

44

P31 The impact of a Comprehensive Geriatric Assessment (CGA) on medical oncology treatment decisions for elderly patients with cancer

A.M. Horgan, N.B. Leighl, S.M.H. Alibhai

Journal:

Critical Reviews in Oncology/Hematology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

45

Diet does not affect intercolonial fighting in Leptothoracine ants

T. M. Alloway, A. Leighl, D. Ryckman

Journal:

Insectes Sociaux

Year:

1991

Language:

english

File:

PDF, 270 KB

english, 1991

46

A phase I pharmacokinetic study of bexarotene with vinorelbine and cisplatin in patients with advanced non-small-cell lung cancer (NSCLC)

Heather A. Wakelee, Gary Middleton, David Dunlop, Rodryg Ramlau, Natasha Leighl, Desiree Hao, Arturo Lopez-Anaya, Petr Zatloukal, Charlotte D. Jacobs

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 284 KB

english, 2012

47

The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer

Heather A. Wakelee, Chris H. Takimoto, Arturo Lopez-Anaya, Quincy Chu, Gary Middleton, David Dunlop, Rodryg Ramlau, Natasha Leighl, Eric K. Rowinsky, Desiree Hao, Petr Zatloukal, Charlotte D. Jacobs,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 393 KB

english, 2012

48

Enhancing decision making about participation in cancer clinical trials: development of a question prompt list

Richard F. Brown, Elyse Shuk, Natasha Leighl, Phyllis Butow, Jamie Ostroff, Shawna Edgerson, Martin Tattersall

Journal:

Supportive Care in Cancer

Year:

2011

Language:

english

File:

PDF, 212 KB

english, 2011

49

A Phase 2 study of perifosine in advanced or metastatic breast cancer

Natasha B. Leighl, Susan Dent, Mark Clemons, Theodore A. Vandenberg, Richard Tozer, David G. Warr, R. Michael Crump, David Hedley, Gregory R. Pond, Janet E. Dancey, Malcolm J. Moore

Journal:

Breast Cancer Research and Treatment

Year:

2008

Language:

english

File:

PDF, 203 KB

english, 2008

50

How Affordable are Targeted Therapies in Non-Small Cell Lung Cancer?

Linda E. Coate, Natasha B. Leighl

Journal:

Current Treatment Options in Oncology

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011